You can find the patterns and step-by-step pictures on my blog
* Coloured beads for the atoms – I chose green for carbon, orange for nitrogen, blue for oxygen and red for hydrogen. choose beads with holes large enough for the wire to pass through 4-5 times.
* Cylinder beads for the bonds. It’s up to you how many beads you choose to use for each bond. I used two, but it you want to make a more open molecule you could use more, or if you have longish cylinder beads then just one bead per bond may work fine.
* Fine beading wire or nylon filament.
* Wire cutters
Lets start with caffeine.
Begin by making a foundation chain, stringing your cylinder beads between each of the beads, in this order: C, N, C, N, C, N, C, N, C.
Thread two more cylinder beads, and thread the wire through the first bead once more to make a ring. Double the wire back through the last two cylinder beads and the last C bead.
String cylinder beads, an oxygen bead, and two more cylinder beads, then pass the wire through the carbon bead a second time, forming a loop. Thread the wire through the next two cylinder beads and the next N bead.
Now for our first methyl group: string 2 cylinder beads, a C, two more cylinder beads and an H. Double the wire back through the last two cylinder beads and the C. String two more cylinder beads and an H, double back through the bond and the carbon atom. Add another hydrogen in the same way, and thread the wire right through the last bond, the C bead, the next bond, the N bead, the next bond and the next C in the ring. You can see the wire goes up through the C bead for the first H, down to make the second, up again for the third, and down again to finish the group.
Make another double-bonded oxygen and another methyl group by repeating the last two steps.
You should now have passed through the fifth bead in the ring, a C bead. Thread two cylinder beads, pass the wire through the first bead in the ring, thread two more cylinder beads, and pass the wire through the fifth bead once more, and then the next bond and the next N bead.
String two more cylinder beads and thread the wire through the next C bead forming a double bond. Thread two cylinder beads and an H, double back through the ond, and pass the wire through the C bead once more, then through the next bond and next N bead.
Add a methyl group to this N bead in the same way as before.
Finish by passing the wire through the last bond in the ring, twist the ends of the wires together, and hide the loose ends by threading them into the neighbouring beads before trimming off.
And there you go, a caffeine molecule!
Capsaicin is a little more complicated, but uses the same techniques.
pattern for beaded capsacin molecule
This time, your foundation start with two cylinder beads and then as follows: 7xC, N, 9xC, H.
Double back through the last bond and the last C, and add two H beads by doubling back and forth as we did to make methyl groups.
Add a methyl group to the next C atom, as we did for caffeine.
At the next C, string 2 cylinder beads and an H, double back through the bond and pass the wire through the C atom in the same direction as we are working. Thread 2 cylinder beads and pass through the next C to form a double bond, and add another H in the same way as for the last bead.
Add 2 H beads to each of the next four C beads by doubling back and forth as before (I apologise for the mistake in the pattern which shows one bead with just 1 H).
Add a double bonded oxygen as we did for the caffeine molecules.
Add one H to the next N bead by stringing two cylinder beads and an H bead, doubling back through the bond and passing the wire through the N in the same direction as we are working.
Add two H beads to the next C. Pass straight through the next C and then make a double bond by threading two cylinder beads and threading through the next C in the chain. Add a single H to the same bead.
Pass through the next C and string two cylinder beads, an oxygen bead, 2 more cylinders and an H. Double all the way back through the whole side chain and pass the wire through the C in the direction we’re working.
Repeat the previous step on the next bead.
beaded capsaicin modelFor the last two beads, add a single H to each and a double bond between them by repeating the fourth step. Finish by passing the wire through the last bond and through the 6th-from-last C (the one with no hydrogens or side chains attached) before fastening off the ends and weaving them into the surrounding beads.